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PRODID:-//Event Calendar 2.0//iCal4j 2.0//EN
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DTSTAMP:20260316T062643Z
DTSTART:20250707T150000
DTEND:20250707T160000
SUMMARY:Prof. Dr. Walter Nickel: Molecular mechanism and machinery driving unconventional secretion of Fibroblast Growth Factor 2 from tumor cells
TZID:Europe/Berlin
UID:event-12484434@events.goettingen-campus.de
LOCATION:Physiologie/Biochemie - Library\, Room 1.122
CONTACT:Susann Meyer\, susann.meyer@med.uni-goettingen.de\, 0551 3961944
CATEGORIES:research
DESCRIPTION:The vast majority of secretory proteins contain N-terminal signal peptides for ER/Golgi-dependent transport into the extracellular space.  Exceptions from this general mode of protein secretion from mammalian cells have been discovered more than 30 years ago\, yet the molecular mechanisms underlying these alternative secretory pathways have remained elusive until recently.  Proteins following such secretory routes have fundamental physiological functions in both health and disease\, with Interleukin 1β and Fibroblast Growth Factor 2 being prime examples.  The discoveries revealing the molecular mechanisms driving unconventional protein secretion did not only solve long-standing problems in molecular cell biology but also paved the way for new strategies for the treatment of for example inflammatory diseases and cancer.\n\nTitle: MBExC Lecture: Molecular mechanism and machinery driving unconventional secretion of Fibroblast Growth Factor 2 from tumor cells\nSpeaker: Prof. Dr. Walter Nickel\nOrganizer: Cluster of Excellence Multiscale Bioimaging (MBExC)\, Zentren und Netzwerke\nHost: Prof. Dr. Peter Rehling\nContact: Susann Meyer\, susann.meyer@med.uni-goettingen.de\, 0551 3961944\n
URL:https://events.goettingen-campus.de/event?eventId=12484434
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